Synthetics will always have the chemical similarity to the cannabinoids found in natural hemp and marijuana. A synthetic cannabinoid binds to the CB1 receptor just like hemp. These synthetic materials are available from a number of source that is studying them and finding ways to develop new materials for drug testing. It will take a lot of help to advance their development as science progresses.
The temps of synthetic (synthetic cannabinoid) materials are between 185 and 262 F. Unlike delta-9 THC, where the actual temperature at which THC is absorbed is typically 195 to 202 F, temps of synthetic materials range around 180-190. This raises good questions:
- How long does the CB1 receptor stay open/stuck open during cannabis use?
- Doesn’t this “set up” for THC to be absorbed long before CB1 is subsumed?
- Or are the temps just too cold looking on the outside to tell?
CB1 receptors are located in the brain, the immune system, the retina, and production of serotonin and dopamine. They also have been used to treat some forms of depression. CB1 is also activated by the endocannabinoid system found in the brain.
Cocaethylene (COC), is a synthetic cannabinoid that acts as an antagonist of CB1, front offered with CB1, and floods the core of the human brain with anandamide, a compound that is analogous to endocannabinoids. The heat is not the only way many reports of synthetic cannabis effects are known to be inaccurate.
Some fellow aggies before me have made some very valid observations about these products on the debates list. From reading the COC product orders, the net-result is that the difficulty of maintenance like installment pays for it, you either got a quality product, or you’re just not that good, the last time I checked. However, your temps should be high enough to make humidity levels less of a problem during your growing season.
These are 2 years into legalization, however many of the adults I have talked to about the latest experiences with the girlfriend or family member being blown away by potency say it’s hard for them to compare to 20 years ago. When they were young, they could smoke enough to get the desired effect without a lot of the high.